At Fanime I did a panel called Anime and Manga For Grownups where I covered many currently available titles which I felt adult fans should be aware of and likely would enjoy.
I was very surprised how many at the panel had not heard of most of these titles.
One requested I post my lists so they could use them as reference material. I did not speak about many of the titles here but the full lists I had with me could be of use to fans.
Fanime 2009: Anime and Manga For Grownups - Anime
Fanime 2009: Anime and Manga For Grownups - Manga